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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC6 All Species: 11.21
Human Site: S528 Identified Species: 22.42
UniProt: O95255 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95255 NP_001162.4 1503 164906 S528 E L G A L R T S G L L F S V S
Chimpanzee Pan troglodytes XP_001145351 1247 137800 G378 I T F S I P E G A L V A V V G
Rhesus Macaque Macaca mulatta XP_001109862 1347 147568 E478 K K R N H H Q E E Q M R Q K D
Dog Lupus familis XP_547113 1504 165780 S529 L G A M R T S S L L F S V S L
Cat Felis silvestris
Mouse Mus musculus Q9R1S7 1498 164770 S526 E L S A L K T S T L L F S V S
Rat Rattus norvegicus O88269 1502 164977 S526 E L G A L K T S A F L F S V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517193 1537 172363 S554 E L K V L K K S A Y L A A V G
Chicken Gallus gallus Q5F364 1525 170953 A542 L K V L K K S A Y L A A M G T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341895 1518 169232 A542 L R V L K K M A Y L G A I S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 L421 S A I S I R D L K A K W D P N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LZJ5 1539 172119 K540 M E F G W L S K F L Y S I A G
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 L525 E L K N L T K L G C Y M A V T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.6 84.9 79.5 N.A. 78.5 78.4 N.A. 45 45.3 N.A. 45.9 N.A. 28.2 N.A. N.A. N.A.
Protein Similarity: 100 55.6 86.8 87.3 N.A. 85.8 86 N.A. 63.5 63.2 N.A. 64.1 N.A. 46.9 N.A. N.A. N.A.
P-Site Identity: 100 13.3 0 13.3 N.A. 80 80 N.A. 40 6.6 N.A. 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 13.3 20 N.A. 86.6 86.6 N.A. 53.3 33.3 N.A. 26.6 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.9 33.8 N.A.
Protein Similarity: N.A. N.A. N.A. 49.5 52.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 25 0 0 0 17 25 9 9 34 17 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 9 % D
% Glu: 42 9 0 0 0 0 9 9 9 0 0 0 0 0 0 % E
% Phe: 0 0 17 0 0 0 0 0 9 9 9 25 0 0 0 % F
% Gly: 0 9 17 9 0 0 0 9 17 0 9 0 0 9 25 % G
% His: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 9 0 17 0 0 0 0 0 0 0 17 0 0 % I
% Lys: 9 17 17 0 17 42 17 9 9 0 9 0 0 9 0 % K
% Leu: 25 42 0 17 42 9 0 17 9 59 34 0 0 0 9 % L
% Met: 9 0 0 9 0 0 9 0 0 0 9 9 9 0 0 % M
% Asn: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 9 0 0 9 0 0 % Q
% Arg: 0 9 9 0 9 17 0 0 0 0 0 9 0 0 0 % R
% Ser: 9 0 9 17 0 0 25 42 0 0 0 17 25 17 25 % S
% Thr: 0 9 0 0 0 17 25 0 9 0 0 0 0 0 25 % T
% Val: 0 0 17 9 0 0 0 0 0 0 9 0 17 50 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 17 9 17 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _